王琪,女,1985年12月,副教授。

主要从事药物载体材料相关领域的研究,着力开展肿瘤靶向性课题以及诊断治疗相结合的最新研究方向,针对肿瘤药物靶向载体材料进行设计,构建新型给药系统。发挥多学科结合的优势,探索和研究生物靶向的前沿理论问题和关键技术难点。

迄今已获得中国发明专利授权5项,美国专利一项。在BiomaterialsNanotoxicologyAutophagyTheronoticsScientific Report 等国际学术期刊上发表24篇论文(被SCI收录20篇),其中以第一或等同第一作者发表论文14篇。


Email:wangqi@ecust.edu.cn
地址:上海市徐汇区梅陇路130号,华东理工大学实验十三楼301室


个人简历
2014.07 - 2014.12上海迈景纳米生物科技有限公司,助理研究员

2015.01 - 2017.04

新加坡南洋理工大学,化学与生物医学工程学院,博士

2017.04 - 2018.06

华东理工大学,化学与分子工程学院,精细化工系,讲师

2018.06 至今

华东理工大学,化学与分子工程学院,精细化工系,副教授

代表性论文
  1. AIE-based nanoaggregate tracker: high-fidelity visualization of lysosomal movement and drug-escaping process, Chemical Scien ce, DOI: 10.1039/D0SC04156D

  2. Trapping endoplasmic reticulum with amphiphilic AIE-active sensor via specific interaction of ATP-sensitive potassium, National Science Review, DOI: nwaa198

  3. Yang Dong, Hongze Liao, Jian Yu, Hao Fu, De Zhao, Ke Gong, Qi Wang,* Yourong Duan,* Incorporation of drug efflux inhibitor and chemotherapeutic agent into an inorganic/organic platform for the effective treatment of multidrug resistant breast cancer, J Nanobiotechnol, 2019, 17, 125.

  4. Qi Wang, Man Luo, Na Wei, Alex Chang, Kathy Qian Luo,* Development of a liposomal formulation of acetyltanshinone IIA for breast cancer therapy, Mol Pharmaceutics, 2019, 16, 3873-3886.

  5. Qi Wang,# Xiangyu Zhang,# Ying Sun, Liting Wang, Li Ding, Wei-Hong Zhu,* Wen Di,* You-Rong Duan,* Gold-caged copolymer nanoparticles as multimodal synergistic photodynamic/ photothermal/chemotherapy platform against lethality androgen-resistant prostate cancer, Biomaterials, 2019, 212, 73-86.

  6. Yang Dong,# Hongze Liao,# Hao Fu,Jian Yu, Qianqian Guo, Qi Wang,* Yourong Duan,* pH-sensitive shell-core platform block DNA repair pathway to amplify irreversible DNA damage of triple negative breast cancer, ACS Appl Mater Interfaces, 2019, 11, 38417-38428.

  7. Jie Zhang,#Qi Wang,# Zhiqian Guo,* Shaoze Zhang, Chenxu Yan, He Tian, Wei-Hong Zhu,* High-fidelity trapping of spatial temporal mitochondria with rational design of aggregation induced emission probes, Adv Func Mater, 2019, 1808153.

  8. Qiang Li, Jun Cao, Qi Wang,* Jie Zhang, Shiqin Zhu, Zhiqian Guo, Wei-Hong Zhu,* Nanomized tumor-microenvironment active NIR fluorescent prodrug for ensuring synchronous occurrences of drug releasing and fluorescence tracing,Journal of Materials Chemistry B, 2019, 7, 1503.

  9. Jie Zhang,#Qi Wang,# Jingkang Liu, Zhiqian Guo,* Jinfeng Yang, Qiang Li, Shaoze Zhang, Chenxu Yan, Wei-Hong Zhu,* Saponin-based near-infrared nanoparticles with aggregation-induced emission behavior: enhancing cell compatibility and permeability, ACS Applied Bio Materials, 2019, 2, 943-951.