王琪,博士,副教授,博士生导师

国家优秀青年基金获得者(2022),上海市“浦江人才”(2018)


研究领域为精细化工(荧光染料)。针对既有荧光染料在生物成像和诊疗应用中灵敏度低、输运准确性差、信号反馈滞后等诸多制约其广泛应用的问题,围绕如何提升荧光生物识别染料诊疗精准度的关键科学问题,借助化学产品工程的原理与方法发展了系列高性能、精细化的荧光染料提升检测准确性,通过研究考察载体材料的热力学驱动与动力学扩散行为构筑了靶向缓控释载体材料提升传递精准度,并深度融合荧光染料和载体材料构建了精准诊疗一体化平台。

先后入选中国抗癌协会纳米肿瘤学专业委员会委员、中国医药生物技术协会造影技术分会委员、上海市药学会会员、上海药学会药剂学青年专委会委员、中国医药卫生文化协会医工融合分会委员。


研究生招生专业:应用化学,生物与医药


研究生招生专业:应用化学

Email:wangqi@ecust.edu.cn
地址:上海市徐汇区梅陇路130号,华东理工大学实验十三楼301室


个人简历
2017.04   至今
华东理工大学,化学与分子工程学院,精细化工系,讲师,副教授
2015.01 - 2017.04新加坡南洋理工大学,化学与生物医学工程学院,博士后
2014.07 - 2014.12上海迈景纳米生物科技有限公司,助理研究员

2011.08 - 2014.07

四川大学,华西药学院,药剂学,博士

2008.08 - 2011.07

四川大学,华西药学院,药剂学,硕士

2004.09 - 2008.07

四川大学,华西药学院,理学学士

代表性论文
  1. Qi Wang, Yang He, Ming Shen, Lili Huang, Li Ding, Jian Hu, Yang Dong, Hao Fu, Quan Wang, Ying Sun, Lin Zhang, Jun Cao, Yourong Duan, Precision embolism: Biocompatible temperature-sensitive hydrogels as novel embolic materials for both mainstream and peripheral vessel, Adv Func Mater,2021;2011170.

  2. Zhirong Zhu, Qi Wang*, Hongze Liao, Ming Liu, Zhenxing Liu, Youheng Zhang, Wei-Hong Zhu*, National Science Review, 2020, DOI: 10.1093/nsr/nwaa198.

  3. Zhenxing Liu, Qi Wang*, Zhirong Zhu, Ming Liu, Xiaolei Zhao and Wei-Hong Zhu, AIE-based nanoaggregate tracker: high-fidelity visualization of lysosomal movement and drug escaping processes, Chem. Sci., 2020, 11, 12755–12763

  4. Jie Zhang,#Qi Wang,# Zhiqian Guo,* Shaoze Zhang, Chenxu Yan, He Tian, Wei-Hong Zhu,* High-fidelity trapping of spatial temporal mitochondria with rational design of aggregation induced emission probes, Adv Func Mater, 2019, 1808153.

  5. Qi Wang,# Xiangyu Zhang,# Ying Sun, Liting Wang, Li Ding, Wei-Hong Zhu,* Wen Di,* You-Rong Duan,* Gold-caged copolymer nanoparticles as multimodal synergistic photodynamic/ photothermal/chemotherapy platform against lethality androgen-resistant prostate cancer, Biomaterials, 2019, 212, 73-86.

  6. Yang Dong,# Hongze Liao,# Hao Fu,Jian Yu, Qianqian Guo, Qi Wang,* Yourong Duan,* pH-sensitive shell-core platform block DNA repair pathway to amplify irreversible DNA damage of triple negative breast cancer, ACS Appl Mater Interfaces, 2019, 11, 38417-38428.

  7. Qiang Li, Jun Cao, Qi Wang,* Jie Zhang, Shiqin Zhu, Zhiqian Guo, Wei-Hong Zhu,* Nanomized tumor-microenvironment active NIR fluorescent prodrug for ensuring synchronous occurrences of drug releasing and fluorescence tracing,Journal of Materials Chemistry B, 2019, 7, 1503.

  8. Qi Wang, Man Luo, Na Wei, Alex Chang, Kathy Qian Luo,* Development of a liposomal formulation of acetyltanshinone IIA for breast cancer therapy, Mol Pharmaceutics, 2019, 16, 3873-3886.

  9. Jie Zhang,#Qi Wang,# Jingkang Liu, Zhiqian Guo,* Jinfeng Yang, Qiang Li, Shaoze Zhang, Chenxu Yan, Wei-Hong Zhu,* Saponin-based near-infrared nanoparticles with aggregation-induced emission behavior: enhancing cell compatibility and permeability, ACS Applied Bio Materials, 2019, 2, 943-951.

  10. Qi Wang,#Xiangyu Zhang,#Hongze Liao, Ying Sun, Li Ding, Yanwei Teng, Wei‐Hong Zhu,* Zhirong Zhang,* Yourong Duan,* Multifunctional shell-core nanoparticles for treatment of multidrug resistance hepatocellular carcinoma, Adv Func Mater, 2018, 14, 1706124.

  11. Qiang Li,#Qi Wang,# Saibo Wang, Shiqin Zhu, Tianwen Yuan, Zhiqian Guo, Jun Cao,* He Tian, Wei-Hong Zhu,* Near-Infrared fluorescent theranostic CiESPtin prodrug with transcatheter intra-arterial therapy: application to rabbit hepatocellular carcinoma, Advanced Therapeutics, 2018, 1800093.

  12. Ying Sun,#Qi Wang,# Jianhua Chen, Lei Liu, Li Ding, Ming Shen, Jin Li,* Baoshan Han,* Yourong Duan,* Temperature-sensitive gold nanoparticle-coated pluronic-PLL nanoparticles for drug delivery and chemo-photothermal therapy, Theranostics, 2017, 18, 4424-4444.

授权及申请专利

  1. 段友容,刘培峰,孙颖,王琪,沈鸣。肿瘤细胞及肿瘤血管双靶向纳米粒、构建方法及应用。授权号: ZL201510503842.3

  2. 朱英杰,王可伟,段友容,王琪。磷酸钙纳米结构空心微球及其制备方法。授权号: ZL200910198813.5

  3. 段友容,孙颖,刘培峰,于晖,亓雪莲,王琪,陈晓炎,李晓昱。聚乙二醇-聚乳酸羟基乙酸-聚赖氨酸纳米递送系统、制备方法及其应用。授权号: ZL200910247576.7

  4. 朱英杰,王可伟,段友容,孙颖,王琪。磷酸钙/嵌段共聚物复合多孔纳米球及其制备方法。授权号:ZL200910055356.4

  5. 朱为宏,王琪,郭志前,李强,刘振兴,徐益升。一种基于聚集诱导发光特征的荧光探针及其测定临界胶束浓度的方法和应用。公开号:CN110028446A

  6. 朱为宏,朱志荣,王琪,刘明,张有恒,刘振兴,李翔宇,赵晓蕾。一种多位点可修饰聚集诱导发光喹啉腈衍生物、制备方法及其应用。申请号:202010787316 .5

  7. 朱为宏,王琪,周体健。喹啉腈衍生物在蛋白质印迹法检测蛋白质的应用及其制备方法。申请号:202011359196.5

  8. 朱为宏,王琪,张有恒。一种用于细胞膜快速免洗成像的双亲性荧光探针。申请号:202011343349.7